North Queensland will be aiming to break into the top-four this year after finishing in fifth place on the ladder in 2024.
Todd Payten will have his work cut out for him though after the club waved goodbye to a trio of veteran stars; Kyle Feldt, Valentine Holmes and Chad Townsend.
The Cowboys face a difficult start to their campaign with some tough matches as well as plenty of travel mixed in, before they will then enjoy a stretch of home matches.
The Sporting News takes a look at North Queensland's 2025 NRL draw below.
2025 PREDICTED TEAM LISTS : Broncos | Raiders | Bulldogs | Dolphins | Sharks | Titans | Sea Eagles | Storm | Knights | Cowboys | Eels | Panthers | Rabbitohs | Dragons | Roosters | Warriors | Tigers
North QLD Cowboys NRL full schedule 2025
| Round | Date | Match | Time | Venue |
| 1 | Sat. March 8 | Sea Eagles vs. Cowboys | 7:35pm (AEDT) | 4 Pines Park |
| 2 | Sat. March 15 | Cowboys vs. Sharks | 5:30pm (AEDT) | Queensland Country Bank Stadium |
| 3 | Fri. March 21 | Broncos vs. Cowboys | 8:05pm (AEDT) | Suncorp Stadium |
| 4 | Sat. March 29 | Cowboys vs. Raiders | 5:30pm (AEDT) | Queensland Country Bank Stadium |
| 5 | Fri. April 4 | Panthers vs. Cowboys | 6:00pm (AEDT) | CommBank Stadium |
| 6 | Sat. April 12 | Rabbitohs vs. Cowboys | 5:30pm (AEST) | Optus Stadium |
| 7 | - | BYE | - | - |
| 8 | Sat. April 26 | Cowboys vs. Titans | 5:30pm (AEST) | Queensland Country Bank Stadium |
| 9 | Sat. May 3 | Warriors vs. Cowboys | 5:30pm (AEST) | Suncorp Stadium |
| 10 | Sat. May 10 | Cowboys vs. Panthers | 7:35pm (AEST) | Queensland Country Bank Stadium |
| 11 | Sat. May 17 | Cowboys vs. Sea Eagles | 5:30pm (AEST) | Queensland Country Bank Stadium |
| 12 | - | BYE | - | - |
| 13 | Sat. May 31 | Cowboys vs. Tigers | 5:30pm (AEST) | Queensland Country Bank Stadium |
| 14 | Fri. June 6 | Storm vs. Cowboys | 6:00pm (AEST) | AAMI Park |
| 15 | Sat. June 14 | Cowboys vs. Dolphins | 7:35pm (AEST) | Queensland Country Bank Stadium |
| 16 | Sun. June 22 | Roosters vs. Cowboys | 4:05pm (AEST) | Allianz Stadium |
| 17 | Sun. June 29 | Titans vs. Cowboys | 4:05pm (AEST) | Cbus Super Stadium |
| 18 | Sat. July 5 | Cowboys vs. Storm | 7:35pm (AEST) | Queensland Country Bank Stadium |
| 19 | Sat. July 12 | Cowboys vs. Bulldogs | 7:35pm (AEST) | Queensland Country Bank Stadium |
| 20 | Thurs. July 17 | Dolphins vs. Cowboys | 7:50pm (AEST) | Suncorp Stadium |
| 21 | Fri. July 25 | Cowboys vs. Dragons | 6:00pm (AEST) | Queensland Country Bank Stadium |
| 22 | Sun. August 3 | Sharks vs. Cowboys | 4:05pm (AEST) | Shark Park |
| 23 | Sun. August 10 | Eels vs. Cowboys | 4:05pm (AEST) | CommBank Stadium |
| 24 | Sun. August 17 | Cowboys vs. Knights | 4:05pm (AEST) | Queensland Country Bank Stadium |
| 25 | Sun. August 24 | Tigers vs. Cowboys | 4:05pm (AEST) | Leichhardt Oval |
| 26 | Sat. August 30 | Cowboys vs. Broncos | 7:35pm (AEST) | Queensland Country Bank Stadium |
| 27 | - | BYE | - | - |
When do the Cowboys have bye rounds in 2025?
North Queensland's bye rounds will be in Round 7, as well as in Round 12 and Round 27.