Has the window closed on San Francisco just yet?
The 49ers saw a lot of change to their personnel during the offseason, which was a longer-than-usual one after their injury-riddled squad went 6-11 and missed the playoffs last year.
The franchise's most notable move was to reward quarterback Brock Purdy with a five-year, $265 million contract extension.
After turning over nearly 20 spots on the roster, the Niners have a much younger group on their hands, but they also have a favorable schedule. If stars like Christian McCaffrey and George Kittle can come back in full force, they could be playoff contenders.
First, they'll start things off with some preseason action.
Here's everything you need to know to watch every 49ers preseason game in 2025.
Where to watch 49ers preseason games 2025
- TV channels: KPIX (local)
- Live streams: Fubo
2025 49ers Preseason games will be broadcast locally on KPIX5, with Greg Papa, Tim Ryan and Dennis O'Donnell on the call.
Fans can also stream all 49ers 2025 preseason games live on Fubo.
Fubo carries all the top leagues and teams, plus popular shows, movies and news for the entire household. Stream ESPN, ABC, CBS, Fox, NBC and 100+ top channels of live TV and sports without cable. (Participating plans only. Taxes and fees may apply.)
49ers preseason schedule 2025
| Date | Matchup | Time (ET) | TV/Live stream |
|---|---|---|---|
| Aug. 9 | Broncos 30, 49ers 9 | — | — |
| Aug. 16 | at Raiders | 4 p.m. | KPIX, Fubo |
| Aug. 23 | vs. Chargers | 8:30 p.m. | KPIX, Fubo |
49ers 2025 schedule for regular season
| Week | Date | Opponent | Kickoff time (ET) | TV channel |
| 1 | Sunday, Sept. 7 | at Seahawks | 4:05 p.m. | Fox |
| 2 | Sunday, Sept. 14 | at Saints | 1 p.m. | Fox |
| 3 | Sunday, Sept. 21 | vs. Cardinals | 4:25 p.m. | Fox |
| 4 | Sunday, Sept. 28 | vs. Jaguars | 4:05 p.m. | Fox |
| 5 | Thursday, Oct. 2 | at Rams | 8:15 p.m. | Prime Video |
| 6 | Sunday, Oct. 12 | at Buccaneers | 1 p.m. | CBS |
| 7 | Sunday, Oct. 19 | vs. Falcons | 8:30 p.m. | NBC |
| 8 | Sunday, Oct. 26 | at Texans | 1 p.m. | Fox |
| 9 | Sunday, Nov. 2 | at Giants | 1 p.m. | CBS |
| 10 | Sunday, Nov. 9 | vs. Rams | 4:25 p.m. | Fox |
| 11 | Sunday, Nov. 16 | at Cardinals | 4:05 p.m. | Fox |
| 12 | Monday, Nov. 24 | vs. Panthers | 8:15 p.m. | ESPN |
| 13 | Sunday, Nov. 30 | at Browns | 1 p.m. | CBS |
| 14 | BYE | — | — | — |
| 15 | Sunday, Dec. 14 | vs. Titans | 4:25 p.m. | Fox |
| 16 | Monday, Dec. 22 | at Colts | 8:15 p.m. | ESPN |
| 17 | Sunday, Dec. 28 | vs. Bears | 8:20 p.m. | NBC |
| 18 | TBD | vs. Seahawks | TBD | TBD |