4-0. That’s our MLB player props record so far this week after another perfect 2-0 slate on Tuesday. Wednesday is a new day, and another chance to bet against the woeful Rockies. Eventually, online sportsbooks are going to realize how dreadful the Colorado pitching staff is and start adjusting the opposing team’s player props, but so far, it hasn’t happened.
That means we are going to continue targeting lineups against the Rockies, and it doesn’t hurt that the white-hot Phillies are still in town, looking for a sixth straight win.
MLB Player Prop Picks for May 21
Bryce Harper Over 2.5 Hits, Runs, and RBI (-120 at Bet365)
Philadelphia has crossed the plate 16 times in the series' first two games versus Colorado, and is in prime position to pile up more runs tonight.
Bryce Harper was one of the catalysts last night, racking up three hits and 2 RBI in a blowout victory. Harper has cleared over 2.5 hits, runs, and RBI in five of his last seven contests, and is slashing .333/.400/.507 in May.
He’s a career .351 hitter at Coors Field, with 8 home runs and 30 RBI, and is making hard contact at a career-high 51.8% clip. Harper and his teammates will face rookie southpaw Carson Palmquist tonight, but don’t let the fact that he’s a lefty dissuade you from backing Harper.
The former MVP is slashing .296/.359/.493 versus left-handed pitching in 2025, and has more home runs against them (4) than he does versus righties (3) in 38 fewer at-bats.
As for Palmquist, tonight will mark just his second career start. His first one was not pretty, as he coughed up 6 hits and 5 runs to the Diamondbacks in only 4 innings of work.
Use the bet365 bonus code TSN365 to grab a $150 bonus for MLB games this week.
Pete Crow-Armstrong Over 1.5 Hits, Runs, and RBI (-130 at bet365)
If you don’t know the name Pete Crow-Armstrong, you might want to familiarize yourself with the Cubs center fielder. The 23-year-old is on an absolute tear to start the 2025 season, ranking top-eight in MLB in home runs and RBI, and top-25 in slugging and OPS.
Crow-Armstrong enters play slashing .393/.393/.679 over the last week, smacking 11 hits, while scoring 6 runs and producing 9 RBI. He’s leading baseball’s highest scoring team in nearly every offensive category, and has cleared 1.5 hits, runs, and RBI in five of his past seven contests.
Crow-Armstrong and the Cubs will battle Miami and the struggling Max Meyer this afternoon.
Meyer has coughed up 25 hits and 18 runs over his last 20.1 innings, and is issuing hard contact at a career-worst 49% rate.
Meyer has faced Crow-Armstrong three times over his short career, yielding a home run and a walk in two of those at-bats.