Luton and Wimbledon kick off the League One season in a clash of two sides who have come from different directions to the division.
The Hatters suffered the ignominy of a second consecutive relegation, while the Dons came up from League Two via the playoffs, with the former favourites for promotion and the latter for relegation this season.
The Football League is as unpredictable as it comes, though, and anything could happen this season as we get underway with an enticing curtain raiser for the campaign.
The Sporting News brings you all the best odds and tips ahead of the opening-night clash.
MORE: Check out the latest odds and predictions for League One 2025/26 season here.
Luton vs. Wimbledon League One prediction
Despite relegation, Luton finished last season strongly last season, winning three of their final four games. They should take that form into the new campaign, and win comfortably against the newly promoted Dons.
They are priced up at 21/50 with Virgin Bet, with Wimbledon way back at 23/50, and the draw at 18/5.
The Sporting News' Score Prediction: Luton 3-0 Wimbledon
- Luton are given a 64% chance to beat Wimbledon inside 90 minutes by Virgin Bet for this clash.
- Learn more about reading odds, different types of bets and the best online betting sites through our how to bet on football guide
Luton vs. Wimbledon predicted lineups
Luton predicted lineup (4-3-3, right to left)
- Keeley (GK) — Walters, Makosso, Andersen, Naismith — Alli, Lonwijk, Clark — Baptiste, Wells, Saville
Injured: Elijah Adebayo, Jacob Brown
Suspended: None
Wimbledon predicted lineup (3-5-2, right to left)
- Bishop (GK) — Harbottle, Ogundere, Johnson — Hippolyte, Smith, Reeves, Hutchinson, Seddon — Stevens, Browne
Injured: None
Suspended: None
Luton vs. Wimbledon latest odds, correct score betting
Our tip of 3-0 is at very decent odds of 9/1, but there is plenty of potential with other scores. You can check out the other most likely scorelines according to the bookies here, with odds via Bet365.
| Result | Odds* |
| Luton 1-0 | 13/2 |
| Luton 2-0 | 6/1 |
| Luton 3-0 | 9/1 |
| Luton 2-1 | 15/2 |
| Draw 1-1 | 15/2 |
*Click odds to bet direct with our selected partners. Odds correct at time of publish.
Back your correct score pick with Bet365 for £30 in free bets from a £10 stake
Luton vs. Wimbledon team news
- Luton are without Elijah Adebayo and Jacob Brown but have new signings Josh Keeley, Kal Naismith, George Saville and Nahki Wells all available.
- Wimbledon also made a notable addition in goal, with Nathan Bishop joining from Sunderland. He will make his debut at Kenilworth Road.
Luton vs. Wimbledon Bet Builder tips
Our bet builder for this game is Luton to win with a -2 handicap and Nakhi Wells to score on his debut, currently available at 10/1 with BetVictor.
You can check out the latest odds and bet direct with our selected partners using the bet builder tool below.
How to watch Luton vs. Wimbledon: Live stream, TV channel
- Date: Friday, August 1
- Venue: Kenilworth Road
- Time: 8:00 p.m. BST
- TV/Stream: Sky Sports Main Event