Alex de Minaur has exited Wimbledon in the Round of 16.
The Australian handled the windy conditions well in the early stages, dropping just one game to the 24-time Grand Slam champion in a dominant first set.
However, the Serbian proved why he is one of the greatest ever to do it, regaining his composure to edge the next two sets.
Both players were well matched, but it was Djokovic who was able to withstand some lengthy baseline rallies.
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The match appeared destined for a deciding set when de Minaur held a 4-1 advantage in the fourth set, although his 36-year-old opponent found form at a critical juncture, winning the next five straight games and taking out the match.
Djokovic's 1-6 6-4 6-4 6-4 victory sends him through to his 16th quarter-final at the All-England Club.
"It wasn't a great start from me ... very windy, very swirly conditions on the court, he was managing better," the 'Djoker' said after the match.
"I didn't have many solutions, but I reset myself in the second [set].
"It was a tough game to close out in the second, but that was maybe a momentum shift where I felt like, okay, I'm back in the game."
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De Minaur reflected on the result in his post-match press conference, labelling his 2025 grass season as "disappointing".
The 26-year-old spent a fortnight away from the tennis court after an early loss at Roland-Garros, and entered Wimbledon without a grass-court win under his belt this year.
"It is a tough one. I’m looking right now at my grass season as a whole as a tad disappointing," de Minaur said.
"There are positives [from this loss, but] at the moment, where I am in my career, it doesn’t completely fulfil me. I want more.
"I want to be on the other side of this match and finish this match coming out on top, because I think that’s the next step in my career.
"If I’m going to make the next step, these are the types of matches that need to start going my way."
Djokovic will face American Ben Shelton in the last eight.
Tournament top seeds Jannik Sinner and Carlos Alcaraz remain alive.