Two old rivals will go head-to-head on Saturday evening, with a clash between Parramatta and Manly set to take place in the middle of a State of Origin-affected round.
Mitchell Moses and Junior Paulo will both be missing for the Eels, who are beginning to find their mojo heading into the back-end of the season after a slow start.
For the Sea Eagles, they will also be without two of their biggest names due to rep commitments, but will bring in Jake Arthur at halfback for an interesting clash against his father and former club.
The match between the Eels and Sea Eagles will kick off at 5.30pm AEST from CommBank Stadium in Sydney.
Here's everything you need to know about the Eels vs Sea Eagles Round 16 NRL clash.
What time is the NRL tonight? Eels vs Sea Eagles kickoff time
Saturday's game between the Parramatta Eels and Manly Sea Eagles will kick off at 5.30pm AEST.
The match will be held at CommBank Stadium in Sydney.
| Sydney/Melbourne | Brisbane | Adelaide | Perth | New Zealand |
| 5.30pm | 5.30pm | 5pm | 3.30pm | 7.30pm |
How to watch or live stream Eels vs Sea Eagles
Fox League will broadcast Saturday's game. Coverage will begin from 2pm AEST.
Kayo Sports will also stream the game live.
Eels vs Sea Eagles Round 16 team lists
| EELS TEAM LIST | SEA EAGLES TEAM LIST |
| 1. Clint Gutherson 14. Luca Moretti | 1. Kaeo Weekes 14. Karl Lawton |
Are you running this weekend? Go further with the ForeverRun NITRO' from PUMA.